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SPS, Moersch-Woltman syndrome

Stiff person syndrome

A rare autoimmune neurological condition causing severe muscle stiffness and spasms.

What it is

SPS is linked to antibodies against GAD and can occur with autoimmune conditions such as type 1 diabetes.

Signs people often notice

  • •Muscle stiffness
  • •Painful spasms
  • •Heightened startle
  • •Posture changes

Who it affects

Rare; more common in adults and often with other autoimmune conditions.

Questions worth asking your clinician

  • ?Could this be SPS?
  • ?Which antibodies are relevant?
  • ?What treatment helps?

This information is general and educational. Always speak to your GP or prescribing clinician before changing medication, starting supplements, or acting on anything you read here.

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